51. Peripheral Vascular Surgery for Large Vessel Vasculitis

  1. Gary S. Hoffman MD, MS4,
  2. Cornelia M. Weyand MD, PhD5,
  3. Carol A. Langford MD, MHS4 and
  4. Jörg J. Goronzy MD, PhD5
  1. Ravi R. Rajani MD1,2 and
  2. Vikram S. Kashyap MD, FACS3

Published Online: 3 MAY 2012

DOI: 10.1002/9781118355244.ch51

Inflammatory Diseases of Blood Vessels, Second Edition

Inflammatory Diseases of Blood Vessels, Second Edition

How to Cite

Rajani, R. R. and Kashyap, V. S. (2012) Peripheral Vascular Surgery for Large Vessel Vasculitis, in Inflammatory Diseases of Blood Vessels, Second Edition (eds G. S. Hoffman, C. M. Weyand, C. A. Langford and J. J. Goronzy), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118355244.ch51

Editor Information

  1. 4

    Department of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland Clinic, Lerner College of Medicine, Cleveland, OH, USA

  2. 5

    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

Author Information

  1. 1

    Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA

  2. 2

    Department of Vascular and Endovascular Surgery, Grady Memorial Hospital, Atlanta, GA, USA

  3. 3

    Division of Vascular Surgery and Endovascular Therapy, University Hospitals Case Medical Center, Cleveland, OH, USA

Publication History

  1. Published Online: 3 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9781444338225

Online ISBN: 9781118355244



  • Takayasu's arteritis;
  • giant cell arteritis;
  • large vessel vasculitis;
  • endovascular surgery;
  • angioplasty;
  • brachiocephalic artery;
  • renal artery;
  • aorta;
  • aneurysm


Takayasu's arteritis (TA) and giant cell arteritis (GCA) are two forms of large vessel vasculitis (LVV) that can result in vascular insufficiency or aneurysm formation necessitating operative therapy. Open surgery and more recently, endovascular intervention, is primarily reserved for cases of end-organ ischemia, worsening cerebrovascular disease or aneurysmal degeneration. Endovascular intervention appears to be well-suited for use in short-segment brachiocephalic or renal lesions, but long-term results regarding durability of patency are scant. Available data indicate superior long-term patency with open reconstruction. Surgical reconstruction has consistently been shown to be well tolerated with a reasonably durable long-term result.