1. Peng-Fei Xu1 and
  2. Wei Wang2
  1. Jun Jiang and
  2. Liu-Zhu Gong

Published Online: 18 OCT 2013

DOI: 10.1002/9781118356654.ch2

Catalytic Cascade Reactions

Catalytic Cascade Reactions

How to Cite

Jiang, J. and Gong, L.-Z. (2013) BRØNSTED ACID–CATALYZED CASCADE REACTIONS, in Catalytic Cascade Reactions (eds P.-F. Xu and W. Wang), John Wiley & Sons, Inc, Hoboken, NJ. doi: 10.1002/9781118356654.ch2

Editor Information

  1. 1

    State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P.R. China

  2. 2

    Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico

Publication History

  1. Published Online: 18 OCT 2013
  2. Published Print: 24 OCT 2013

ISBN Information

Print ISBN: 9781118016022

Online ISBN: 9781118356654



  • Brønsted acids-catalyzed cascade reactions;
  • protonic acid–catalyzed cascade reactions;
  • thiourea (urea)–catalyzed cascade reactions;
  • transition metal–catalyzed cascade reaction


This chapter focuses on the important advances made in chiral Brønsted acid–catalyzed asymmetric cascade reactions. The main body of the chapter is divided into three parts based on the chemical nature of the catalysts: (1) protonic acid–catalyzed cascade reactions, (2) Thiourea (urea)–catalyzed cascade reactions, and (3) cooperative Brønsted acid– and transition metal–catalyzed cascade reactions. The chapter also focuses on reactions that utilized combinations of chiral Brønsted acids and different transition metal catalysts via dual or sequential activation approaches.