4. GOLD-CATALYZED CASCADE REACTIONS

  1. Peng-Fei Xu1 and
  2. Wei Wang2
  1. Yanzhao Wang and
  2. Liming Zhang

Published Online: 18 OCT 2013

DOI: 10.1002/9781118356654.ch4

Catalytic Cascade Reactions

Catalytic Cascade Reactions

How to Cite

Wang, Y. and Zhang, L. (2013) GOLD-CATALYZED CASCADE REACTIONS, in Catalytic Cascade Reactions (eds P.-F. Xu and W. Wang), John Wiley & Sons, Inc, Hoboken, NJ. doi: 10.1002/9781118356654.ch4

Editor Information

  1. 1

    State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P.R. China

  2. 2

    Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico

Publication History

  1. Published Online: 18 OCT 2013
  2. Published Print: 24 OCT 2013

ISBN Information

Print ISBN: 9781118016022

Online ISBN: 9781118356654

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Keywords:

  • alkenes;
  • alkynes;
  • allenes;
  • cascade reaction;
  • catalysis;
  • cyclopropenes;
  • gold

Summary

This chapter presents an organized collection of representative reactions that highlight the versatilities and synthetic potential of gold catalysis. In particular, those that deliver structural motifs of high synthetic value are favored. Arylalkynes with nucleophilic groups attached ortho to the C-C triple bond often serve as “privileged” substrates for gold catalysis, due to the forced proximity of reacting partners and often beneficiary conjugation between them. Allenes comprise the second class of privileged substrates for gold catalysis. They can be transformed into various functionalized structures, many via cascade processes. In the presence of gold complexes, cyclopropenes can be converted into synthetically versatile alkenyl gold carbene intermediates, which can be of high synthetic utility.