4. GOLD-CATALYZED CASCADE REACTIONS
- Peng-Fei Xu1 and
- Wei Wang2
Published Online: 18 OCT 2013
Copyright © 2014 John Wiley & Sons, Inc.
Catalytic Cascade Reactions
How to Cite
Wang, Y. and Zhang, L. (2013) GOLD-CATALYZED CASCADE REACTIONS, in Catalytic Cascade Reactions (eds P.-F. Xu and W. Wang), John Wiley & Sons, Inc, Hoboken, NJ. doi: 10.1002/9781118356654.ch4
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P.R. China
Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico
- Published Online: 18 OCT 2013
- Published Print: 24 OCT 2013
Print ISBN: 9781118016022
Online ISBN: 9781118356654
- cascade reaction;
This chapter presents an organized collection of representative reactions that highlight the versatilities and synthetic potential of gold catalysis. In particular, those that deliver structural motifs of high synthetic value are favored. Arylalkynes with nucleophilic groups attached ortho to the C-C triple bond often serve as “privileged” substrates for gold catalysis, due to the forced proximity of reacting partners and often beneficiary conjugation between them. Allenes comprise the second class of privileged substrates for gold catalysis. They can be transformed into various functionalized structures, many via cascade processes. In the presence of gold complexes, cyclopropenes can be converted into synthetically versatile alkenyl gold carbene intermediates, which can be of high synthetic utility.