4. Glycine, Serine and the One-Carbon Pool
Published Online: 2 JUL 2012
DOI: 10.1002/9781118357514.ch4
Copyright © 2012 John Wiley & Sons, Ltd
Book Title
Amino Acid Metabolism, Third Edition
Additional Information
How to Cite
Bender, D. A. (2012) Glycine, Serine and the One-Carbon Pool, in Amino Acid Metabolism, Third Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118357514.ch4
Publication History
- Published Online: 2 JUL 2012
- Published Print: 10 AUG 2012
ISBN Information
Print ISBN: 9780470661512
Online ISBN: 9781118357514
- Summary
- Chapter
- References
Keywords:
- glycine, serine and the one-carbon pool;
- glycine role in protein synthesis, creatine synthesis precursor;
- metabolic sources of glycine;
- glycine and serine, and serine as precursor in gluconeogenesis;
- hydroxymethyltransferase, pyridoxal phosphate-dependent aldolase;
- glycine cleavage, mitochondrial multi-enzyme and oxidative decarboxylation;
- non-ketotic hyperglycinaemia, and glycine cleavage system defect;
- glycine and serine, one-carbon units for biosynthetic reactions;
- serine catabolism, metabolic fate of serine;
- selenocysteine termination/insertion, next base after UGA codon
Summary
This chapter contains sections titled:
Sources of glycine
The interconversion of glycine and serine
Glycine oxidase and glyoxylate metabolism
One-carbon metabolism
Serine biosynthesis
Serine catabolism
Peptidyl glycine hydroxylase (peptide α-amidase)
5-Aminolevulinic acid and porphyrin synthesis
Selenocysteine
Further reading