8. Histidine

  1. David A Bender

Published Online: 2 JUL 2012

DOI: 10.1002/9781118357514.ch8

Amino Acid Metabolism, Third Edition

Amino Acid Metabolism, Third Edition

How to Cite

Bender, D. A. (2012) Histidine, in Amino Acid Metabolism, Third Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118357514.ch8

Author Information

  1. University College, London, UK

Publication History

  1. Published Online: 2 JUL 2012
  2. Published Print: 10 AUG 2012

ISBN Information

Print ISBN: 9780470661512

Online ISBN: 9781118357514



  • histidine;
  • histidine role in enzymes, pKa and environment in protein;
  • histidine biosynthetic pathway, histidine biosynthesis and sequence homology;
  • phosphoribosyl-ATP diphosphatase, hydrolysis of phosphoribosyl-ATP;
  • histidinol dehydrogenase inhibitors, chemotherapeutic agents for brucellosis;
  • transamination, minor pathways of histidine catabolism;
  • urocanic acid pathway of histidine catabolism;
  • histidine load test (FIGLU) for folate nutritional status;
  • hydantoin propionate pathway of histidine catabolism;
  • histamine catabolism, oxidation and methyltransferase competition, absent


This chapter contains sections titled:

  • Biosynthesis of histidine

  • Histidine catabolism

  • Histamine

  • Methylhistidine

  • Carnosine and related histidine-containing peptides

  • Further reading