9. The Aromatic Amino Acids: Phenylalanine, Tyrosine and Tryptophan

  1. David A Bender

Published Online: 2 JUL 2012

DOI: 10.1002/9781118357514.ch9

Amino Acid Metabolism, Third Edition

Amino Acid Metabolism, Third Edition

How to Cite

Bender, D. A. (2012) The Aromatic Amino Acids: Phenylalanine, Tyrosine and Tryptophan, in Amino Acid Metabolism, Third Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118357514.ch9

Author Information

  1. University College, London, UK

Publication History

  1. Published Online: 2 JUL 2012
  2. Published Print: 10 AUG 2012

ISBN Information

Print ISBN: 9780470661512

Online ISBN: 9781118357514



  • aromatic amino acids, phenylalanine, tyrosine, tryptophan biosynthesis;
  • aromatic amino acids, dietary, essential amino acids for animals;
  • mammals, and lack of shikimate pathway, enzymes as targets for herbicides;
  • shikimic acid, chemical synthesis of Tamiflu, a neuraminidase inhibitor;
  • dehydroquinate dehydratase, bifunctional with shikimate dehydrogenase;
  • phenylpropanoid pathway in lignin biosynthesis;
  • phenylalanine hydroxylase, for tyrosine synthesis;
  • phenylalanine hydroxylase, inhibition by catecholamines chelating catalytic iron;
  • mammalian catabolism of phenylalanine, hydroxylation to tyrosine;
  • kynurenine pathway, tryptophan catabolism and synthesis in NAD/NADP


This chapter contains sections titled:

  • Biosynthesis of phenylalanine, tyrosine and tryptophan

  • Metabolism of phenylalanine and tyrosine

  • Catabolism of phenylalanine and tyrosine

  • Metabolism of tryptophan

  • Quinone cofactors in amine oxidases

  • Further reading