18. Heterocycles in Medicine

  1. John A. Joule1 and
  2. Keith Mills2

Published Online: 6 AUG 2012

DOI: 10.1002/9781118380208.ch18

Heterocyclic Chemistry at a Glance, Second Edition

Heterocyclic Chemistry at a Glance, Second Edition

How to Cite

Joule, J. A. and Mills, K. (2012) Heterocycles in Medicine, in Heterocyclic Chemistry at a Glance, Second Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118380208.ch18

Author Information

  1. 1

    The School of Chemistry, The University of Manchester, UK

  2. 2

    Independent Consultant, UK

Publication History

  1. Published Online: 6 AUG 2012
  2. Published Print: 4 SEP 2012

ISBN Information

Print ISBN: 9780470971222

Online ISBN: 9781118380208

SEARCH

Keywords:

  • heterocycles in medicine;
  • medicinal chemistry, how drugs function;
  • heterocycles, building blocks for (medicinal) drugs;
  • drugs and ‘trivial’ generic names;
  • stages,‘invention’ and commercialisation of drugs;
  • major neurotransmitters, acting in peripheral/and CNS;
  • acetylcholine mediating, at muscarinic and nicotinic;
  • anticholinesterase agents;
  • adrenaline/noradrenaline in cardiovascular;
  • drugs acting specifically on CNS

Summary

This chapter contains sections titled:

  • Medicinal chemistry – how drugs function

  • Drug discovery

  • Drug development

  • The neurotransmitters

  • Histamine

  • Acetylcholine (ACh)

  • Anticholinesterase agents

  • 5-Hydroxytryptamine (5-HT) (serotonin)

  • Adrenaline and noradrenaline

  • Other significant cardiovascular drugs

  • Drugs acting specifically on the CNS

  • Other enzyme inhibitors

  • Anti-infective agents

  • Antiparasitic drugs

  • Antibacterial drugs

  • Antiviral drugs

  • Anticancer drugs

  • Photochemotherapy