28. Molecular Aspects of Dietary–Exercise Regimen for the Prevention of Metabolic Syndrome

  1. Tahira Farooqui and
  2. Akhlaq A. Farooqui
  1. WATARU AOI

Published Online: 11 OCT 2013

DOI: 10.1002/9781118395318.ch28

Metabolic Syndrome and Neurological Disorders

Metabolic Syndrome and Neurological Disorders

How to Cite

AOI, W. (2013) Molecular Aspects of Dietary–Exercise Regimen for the Prevention of Metabolic Syndrome, in Metabolic Syndrome and Neurological Disorders (eds T. Farooqui and A. A. Farooqui), John Wiley & Sons Ltd, Chichester, UK. doi: 10.1002/9781118395318.ch28

Author Information

  1. Kyoto Prefectural University, Kyoto, Japan

Publication History

  1. Published Online: 11 OCT 2013
  2. Published Print: 15 NOV 2013

ISBN Information

Print ISBN: 9781118395271

Online ISBN: 9781118395318

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Keywords:

  • cancer;
  • cardiovascular disease (CVD);
  • diabetes;
  • dietary—exercise regimen;
  • metabolic organs;
  • metabolic syndrome

Summary

Epidemiological studies have shown that dietary—exercise regimen reduces the risk of cardiovascular disease (CVD), type 2 diabetes, and cancer relating to metabolic syndrome. Metabolic function in skeletal muscle, a major consumer of nutrients, is a key factor that can prevent metabolic syndrome. Growing evidence has demonstrated the molecular mechanisms underlying the benefits of a single bout and regular exercise. Exercise improves glucose and lipid metabolic capacity and prevents loss of muscle mass, which occurs along with changes in the expression/activity of muscle proteins. Other organs including adipose tissue, liver, and arterial vein are also functionally and structurally improved by exercise. Myokines, functional proteins that are secreted from muscle into circulation in response to exercise, partly mediate as a metabolic regulator of the metabolic organs.