28. General Surgical Management of Patients with Hemophilia

  1. Christine A. Lee MA, MD, DSc, FRCP, FRCPath, FRCOG2,
  2. Erik E. Berntorp MD, PhD3 and
  3. W. Keith Hoots MD4
  1. Cindy Leissinger and
  2. Rebecca Kruse-Jarres

Published Online: 24 APR 2014

DOI: 10.1002/9781118398258.ch28

Textbook of Hemophilia, 3

Textbook of Hemophilia, 3

How to Cite

Leissinger, C. and Kruse-Jarres, R. (2014) General Surgical Management of Patients with Hemophilia, in Textbook of Hemophilia, 3 (eds C. A. Lee, E. E. Berntorp and W. K. Hoots), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118398258.ch28

Editor Information

  1. 2

    Emeritus Professor of Haemophilia, University of London, London, UK

  2. 3

    Professor of Coagulation Medicine, Lund University, Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden

  3. 4

    Director, Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA

Author Information

  1. Tulane University School of Medicine, Louisiana, USA

Publication History

  1. Published Online: 24 APR 2014
  2. Published Print: 23 MAY 2014

ISBN Information

Print ISBN: 9781118398241

Online ISBN: 9781118398258



  • Surgery;
  • factor IX;
  • factor VIII;
  • desmopressin;
  • antifibrinolytic therapy


Surgery in patients with hemophilia requires a specialized team approach and a hospital capable of supporting intense factor concentrate use and timely laboratory monitoring. The optimal approach utilizes the coordination and resources of the comprehensive hemophilia treatment center team working closely with the surgeon and anesthesiologist. With planning, teamwork, and careful postoperative follow-up, both major and minor nonorthopedic procedures are routinely performed with high rates of success.