3. Reactions Involving Dehydrogenases

  1. Daniela Gamenara1,
  2. Gustavo A. Seoane1,
  3. Patricia Saenz-Méndez2 and
  4. Pablo Domínguez de María3

Published Online: 24 SEP 2012

DOI: 10.1002/9781118409343.ch3

Redox Biocatalysis: Fundamentals and Applications

Redox Biocatalysis: Fundamentals and Applications

How to Cite

Gamenara, D., Seoane, G. A., Saenz-Méndez, P. and de María, P. D. (2012) Reactions Involving Dehydrogenases, in Redox Biocatalysis: Fundamentals and Applications, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118409343.ch3

Author Information

  1. 1

    Organic Chemistry Department, Facultad de Química, UdelaR, Montevideo, Uruguay

  2. 2

    Computational Chemistry and Biology Group, DETEMA and Organic Chemistry Department Facultad de Química, UdelaR Montevideo, Uruguay

  3. 3

    Institut für Technische und Madromolekulare Chemie (ITMC), RWTH Aachen University Aachen, Germany

Publication History

  1. Published Online: 24 SEP 2012
  2. Published Print: 12 OCT 2012

ISBN Information

Print ISBN: 9780470874202

Online ISBN: 9781118409343



  • reactions involving dehydrogenases;
  • dehydrogenases, enzymes catalyzing reversible redox reactions;
  • prochiral carbonyl group biocatalytic reduction;
  • two-step-three-enzyme for key intermediate in atorvastatin;
  • enzymatic redox-reactions and C–C double bond reduction


This chapter contains sections titled:

  • General Considerations

  • Reduction of Carbonyl Groups

  • Racemization and Deracemization Reactions

  • Preparation of Amines

  • Reduction of C–C Double Bonds

  • Oxidation Reactions

  • Dehydrogenase-Catalyzed Redox Reactions in Natural Products

  • Concluding Remarks

  • References