10. Gastrointestinal Lymphoma

  1. Janusz Jankowski MB ChB, MSc, MD, PhD, FRCP, FACG, AGAF2,3,4 and
  2. Ernest Hawk MD, MPH5
  1. Eliza A. Hawkes,
  2. Andrew Wotherspoon and
  3. David Cunningham

Published Online: 15 NOV 2012

DOI: 10.1002/9781118423318.ch10

Handbook of Gastrointestinal Cancer

Handbook of Gastrointestinal Cancer

How to Cite

Hawkes, E. A., Wotherspoon, A. and Cunningham, D. (2012) Gastrointestinal Lymphoma, in Handbook of Gastrointestinal Cancer (eds J. Jankowski and E. Hawk), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118423318.ch10

Editor Information

  1. 2

    Sir James Black Professor of Gastrointestinal Biology and Trials, Centre for Digestive Diseases, Barts and Th e London School of Medicine and Dentistry, London, UK

  2. 3

    Consultant Gastroenterologist, University Hospitals of Leicester, Leicester, UK

  3. 4

    James Black Senior Fellow, University of Oxford, Oxford, UK

  4. 5

    Vice President and Division Head, Division of Cancer Prevention & Population Sciences, Boone Pickens Distinguished Chair for Early Prevention of Cancer, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Author Information

  1. Royal Marsden Hospital, London and Surrey, UK

Publication History

  1. Published Online: 15 NOV 2012
  2. Published Print: 12 JUL 2012

ISBN Information

Print ISBN: 9780470656242

Online ISBN: 9781118423318



  • Lymphoma;
  • extranodal;
  • gastrointestinal;
  • MALT;
  • diffuse large B-cell lymphoma;
  • enteropathy-associated T-cell lymphoma;
  • Burkitt lymphoma;
  • follicular lymphoma;
  • mantle cell lymphoma;
  • chemotherapy


The gastrointestinal (GI) tract is the most common site of extranodal lymphoma. Primary GI lymphoma is relatively rare and can involve any part of the gut, with the stomach being the most common site. Several lymphoma subtypes have a predilection for involving the GI tract. The most common are extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue and diffuse large B-cell lymphoma. However, Burkitt lymphoma, enteropathy-associated T-cell lymphoma, follicular lymphoma, and mantle cell lymphoma are also discussed here due to their propensity for GI involvement.