6. Polymeric Drug Delivery Systems for Encapsulating Hydrophobic Drugs

  1. Dennis Douroumis1 and
  2. Alfred Fahr2
  1. Dagmar Fischer

Published Online: 4 FEB 2013

DOI: 10.1002/9781118444726.ch6

Drug Delivery Strategies for Poorly Water-Soluble Drugs

Drug Delivery Strategies for Poorly Water-Soluble Drugs

How to Cite

Fischer, D. (2013) Polymeric Drug Delivery Systems for Encapsulating Hydrophobic Drugs, in Drug Delivery Strategies for Poorly Water-Soluble Drugs (eds D. Douroumis and A. Fahr), John Wiley & Sons Ltd, Oxford, UK. doi: 10.1002/9781118444726.ch6

Editor Information

  1. 1

    School of Science, University of Greenwich, UK

  2. 2

    Friedrich-Schiller University of Jena, Germany

Publication History

  1. Published Online: 4 FEB 2013
  2. Published Print: 21 JAN 2013

ISBN Information

Print ISBN: 9780470711972

Online ISBN: 9781118444726

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Keywords:

  • in situ polymerization;
  • emulsion polymerization;
  • interfacial polymerization;
  • interfacial condensation;
  • radical polymerization;
  • miniemulsion;
  • nanospheres;
  • nanocapsules;
  • tank reactors

Summary

The second chapter on polymeric drug delivery systems focuses on techniques that produce particles by in situ polymerization of monomers. It provides a description of the preparation techniques, followed by a discussion of nanospheres and nanocapsules produced by these techniques. The effect of formulation components and process parameters on particle morphology is also covered. Finally, toxicological aspects for in vivo application and scale-up aspects are highlighted.