110. Craniofacial Disorders Affecting the Dentition: Genetic

  1. Clifford J. Rosen MD
  1. Yong-Hee P. Chun,
  2. Paul H. Krebsbach and
  3. James P. Simmer

Published Online: 19 JUL 2013

DOI: 10.1002/9781118453926.ch110

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

How to Cite

Chun, Y.-H. P., Krebsbach, P. H. and Simmer, J. P. (2013) Craniofacial Disorders Affecting the Dentition: Genetic, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition (ed C. J. Rosen), John Wiley & Sons, Inc., Ames, USA. doi: 10.1002/9781118453926.ch110

Publication History

  1. Published Online: 19 JUL 2013

ISBN Information

Print ISBN: 9781118453889

Online ISBN: 9781118453926

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Keywords:

  • craniofacial malformations;
  • dentition;
  • genetic disorders;
  • mineral metabolism;
  • oral abnormality;
  • palate

Summary

Changes in the dentition and its supporting oral structures may occur in response to disorders of mineral metabolism. This chapter provides a concise overview of the dental manifestations of selected disorders of bone and mineral metabolism, including genetic disorders affecting the number of teeth, dentin, and enamel. The initiation of tooth development depends on interactions between oral epithelium and mesenchyme derived from cranial neural crest cells. Cleft lip and/or palate are relatively common craniofacial malformations that can have profound impact on nutritional, speech, dental, and psychological development. Metabolic diseases of bone are disorders of bone remodeling that characteristically involve the entire skeleton and are often manifest in the oral cavity, which can lead to the diagnosis of the underlying systemic disease.