30. DXA in Adults and Children

  1. Clifford J. Rosen MD
  1. Glen Blake,
  2. Judith E. Adams and
  3. Nick Bishop

Published Online: 19 JUL 2013

DOI: 10.1002/9781118453926.ch30

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

How to Cite

Blake, G., E. Adams, J. and Bishop, N. (2013) DXA in Adults and Children, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition (ed C. J. Rosen), John Wiley & Sons, Inc., Ames, USA. doi: 10.1002/9781118453926.ch30

Publication History

  1. Published Online: 19 JUL 2013

ISBN Information

Print ISBN: 9781118453889

Online ISBN: 9781118453926

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Keywords:

  • areal bone mineral density (BMDa);
  • dual-energy X-ray absorptiometry (DXA);
  • fracture risk assessment tool (FRAX)

Summary

Dual-energy X-ray absorptiometry (DXA) is the most widely used method of measuring areal bone mineral density (BMDa) in adults and children and provides precise results with very low doses of ionizing radiation. The basic rationale for DXA examinations is their ability to identify patients at increased risk of fracture, and the new World Health Organization (WHO) fracture risk assessment tool (FRAX) effectively exploits this ability and sets the clinical application of bone densitometry on a sound scientific basis. One merit of the FRAX scheme is that it treats BMDa measurements as just another type of clinical risk factor rather than a uniquely special indicator of skeletal status. There are particular issues with interpreting DXA results in children in whom the dependency on bone size is a limitation, and to date there is no consensus on whether size correction should be applied and which method is optimum.