32. Magnetic Resonance Imaging of Bone

  1. Clifford J. Rosen MD
  1. Sharmila Majumdar

Published Online: 19 JUL 2013

DOI: 10.1002/9781118453926.ch32

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

How to Cite

Majumdar, S. (2013) Magnetic Resonance Imaging of Bone, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition (ed C. J. Rosen), John Wiley & Sons, Inc., Ames, USA. doi: 10.1002/9781118453926.ch32

Publication History

  1. Published Online: 19 JUL 2013

ISBN Information

Print ISBN: 9781118453889

Online ISBN: 9781118453926

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Keywords:

  • bone strength;
  • cortical bone;
  • magnetic resonance imaging (MRI);
  • osteoporotic status;
  • therapeutic response;
  • trabecular bone

Summary

Three-dimensional (3D) imaging techniques that reveal bone structure are emerging as important contenders for defining bone quality, at least partially. Magnetic resonance imaging (MRI) has been used in addition to X-rays, computed tomography (CT), and bone scintigraphy to detect insufficiency fractures, stress fractures, and metastatic fractures. A recent development in MR is in the assessment of trabecular bone and cortical bone structure that makes it possible to obtain noninvasive bone biopsies at multiple anatomic sites. T2* methods have been used to quantify trabecular bone, and these measures have been related to bone strength, osteoporotic status, and therapeutic response. In this chapter, the relationship between, age, fracture status, and even post-therapeutic response is discussed. New advances in peripheral CT, MR are ongoing and evolving at a rapid pace, and with the establishment of robust analysis methodologies and normative databases, they have the potential for further clinical utilization in the coming years.