63. Premenopausal Osteoporosis

  1. Clifford J. Rosen MD
  1. Adi Cohen and
  2. Elizabeth Shane

Published Online: 19 JUL 2013

DOI: 10.1002/9781118453926.ch63

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

How to Cite

Cohen, A. and Shane, E. (2013) Premenopausal Osteoporosis, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition (ed C. J. Rosen), John Wiley & Sons, Inc., Ames, USA. doi: 10.1002/9781118453926.ch63

Publication History

  1. Published Online: 19 JUL 2013

ISBN Information

Print ISBN: 9781118453889

Online ISBN: 9781118453926

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Keywords:

  • bisphosphonates;
  • bone mineral density (BMD);
  • glucocorticoid-induced osteoporosis;
  • low trauma fracture;
  • premenopausal osteoporosis

Summary

This chapter discusses issues specific to the diagnosis, clinical evaluation, and management of pre-menopausal women present with low trauma fracture and/or low bone mineral density (BMD). In postmenopausal women, osteoporosis may be diagnosed before a fracture has occurred by using BMD T-scores. The main goal of the evaluation of a premenopausal woman with low-trauma fractures or low BMD is to identify any secondary cause. In most, a secondary cause can be found, the most common being glucocorticoid excess, anorexia nervosa, premenopausal estrogen deficiency, and celiac disease. Although pharmacologic therapy is rarely justified in premenopausal women, those with an ongoing cause of bone loss and those who have had or continue to have low trauma fractures may require pharmacological intervention, such as bisphosphonates or teriparatide.