67. Approach to Parathyroid Disorders

  1. Clifford J. Rosen MD
  1. John P. Bilezikian

Published Online: 19 JUL 2013

DOI: 10.1002/9781118453926.ch67

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition

How to Cite

Bilezikian, J. P. (2013) Approach to Parathyroid Disorders, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Eighth Edition (ed C. J. Rosen), John Wiley & Sons, Inc., Ames, USA. doi: 10.1002/9781118453926.ch67

Publication History

  1. Published Online: 19 JUL 2013

ISBN Information

Print ISBN: 9781118453889

Online ISBN: 9781118453926

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Keywords:

  • hypocalcemia;
  • hypoparathyroidism;
  • intrinsic functional abnormalities;
  • parathyroid disorders;
  • primary hyperparathyroidism (PHPT)

Summary

The primary parathyroid disorders, in which parathyroid glandular activity is intrinsically abnormal (e.g., primary hyperparathyroidism, hypoparathyroidism) and the secondary parathyroid disorders, in which increased or decreased parathyroid glandular activity is a normal adjustment to another pathophysiological process (e.g., vitamin D deficiency, chronic renal disease), have given us new insights into the importance of parathyroid hormone (PTH) not only in the regulation of the serum calcium concentration but also in terms of skeletal health. This chapter presents an approach to the primary and secondary parathyroid disorders. Primary hyperparathyroidism (PHPT) is the classic endocrine disorder associated with parathyroid gland hyperfunction. Hypoparathyroidism presents a contrast with its more common counterpart in another way, namely in terms of symptomatology. The PTH assay helps to distinguish between hypocalcemia due to a hypoparathyroid state and hypocalcemic conditions associated with a normal physiological response to hypocalcemia.