31. Disulfiram for the Treatment of Cocaine Dependence1

  1. Iosief Abraha1 and
  2. Cristina Cusi2

Published Online: 13 AUG 2012

DOI: 10.1002/9781118454503.ch31

Alcohol and Drug Misuse

Alcohol and Drug Misuse

How to Cite

Abraha, I. and Cusi, C. (2012) Disulfiram for the Treatment of Cocaine Dependence1, in Alcohol and Drug Misuse, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118454503.ch31

Author Information

  1. 1

    Regional Health Authority of Umbria, Perugia, Italy

  2. 2

    Outpatient Services – Neurology, Clinical Institutes of Specialisation, Milan, Italy

Publication History

  1. Published Online: 13 AUG 2012
  2. Published Print: 7 AUG 2012

ISBN Information

Print ISBN: 9780470659694

Online ISBN: 9781118454503



  • disulfiram for treatment of cocaine dependence;
  • disulfiram, and its effectiveness in cocaine dependence;
  • cocaine use, disorder dependence/medical/psychological/social problems;
  • disulfiram, interfering with enzymes involved with cerebral monoamines;
  • disulfiram, on mesolimbic circuits disrupted by cocaine addiction;
  • primary outcomes, drop-outs/rates of side effects/primary substance;
  • cocaine dependents diagnosed by DSM-IV-TR;
  • cocaine dependence, and no pharmacology of proven efficacy;
  • evidence low, on clinical use of disulfiram in cocaine dependence


This chapter contains sections titled:

  • Reference