40. Methadone at Tapered Doses for the Management of Opioid Withdrawal1

  1. Iosief Abraha1 and
  2. Cristina Cusi2

Published Online: 13 AUG 2012

DOI: 10.1002/9781118454503.ch40

Alcohol and Drug Misuse

Alcohol and Drug Misuse

How to Cite

Abraha, I. and Cusi, C. (2012) Methadone at Tapered Doses for the Management of Opioid Withdrawal1, in Alcohol and Drug Misuse, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118454503.ch40

Author Information

  1. 1

    Regional Health Authority of Umbria, Perugia, Italy

  2. 2

    Outpatient Services – Neurology, Clinical Institutes of Specialisation, Milan, Italy

Publication History

  1. Published Online: 13 AUG 2012
  2. Published Print: 7 AUG 2012

ISBN Information

Print ISBN: 9780470659694

Online ISBN: 9781118454503



  • methadone at tapered doses in opioid withdrawal;
  • effectiveness of tapered methadone in managing opioid withdrawal;
  • managed withdrawal/detoxification, by itself, not as treatment for dependence;
  • detoxification, required steps for longer term treatment;
  • methadone at tapered doses versus placebo for detoxification;
  • opioid users in short-term tapered methadone, and heroin withdrawal;
  • limitations, variations in treatment regimes hindering meta-analysis


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  • Reference