35. Medical Comorbidity in Epilepsy

  1. John W. Miller MD, PhD Director, UW Regional Epilepsy Center, Professor of Neurology and Neurological Surgery3 and
  2. Howard P. Goodkin MD, PhD The Shure Professor of Neurology and Pediatrics, Director, Division of Pediatric Neurology4
  1. Kimberly L. Pargeon1 and
  2. Sheryl R. Haut2

Published Online: 10 JAN 2014

DOI: 10.1002/9781118456989.ch35



How to Cite

Pargeon, K. L. and Haut, S. R. (2014) Medical Comorbidity in Epilepsy, in Epilepsy (eds J. W. Miller and H. P. Goodkin), John Wiley & Sons, Oxford. doi: 10.1002/9781118456989.ch35

Editor Information

  1. 3

    University of Washington, Seattle, WA, USA

  2. 4

    Department of Neurology, University of Virginia, Charlottesville, VA, USA

Author Information

  1. 1

    Epilepsy Management Center, Einstein-Montefiore, Bronx, NY, USA

  2. 2

    Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA

Publication History

  1. Published Online: 10 JAN 2014
  2. Published Print: 14 FEB 2014

ISBN Information

Print ISBN: 9781118456941

Online ISBN: 9781118456989



  • epilepsy;
  • medical comorbidity;
  • migraine;
  • stroke;
  • bone health;
  • metabolic disorders;
  • vascular disease


Patients with epilepsy frequently have comorbid medical conditions that can significantly affect quality of life as well as the treatment of their seizures. These comorbid conditions may coexist with epilepsy related to a common pathogenesis; they may arise as a direct result of epilepsy treatment; or they may be unrelated to the epilepsy but complicate its treatment. This chapter briefly discusses some of the interactions between epilepsy and its treatments with some of the more common comorbid conditions, including migraine, vascular disease, bone disease, reproductive disorders, and metabolic disorders.