1. Uncommon Tumors of the Kidney

  1. Derek Raghavan MD, PhD, FACP, FRACP, FASCO President, Professor/Medicine4,
  2. Charles D. Blanke MD, FACP, FRCPC, FASCO Vice-President, Professor and Chief5,
  3. David H. Johnson MD6,
  4. Paul L. Moots MD Associate Professor of Neurology and Medicine, Chief7,
  5. Gregory H. Reaman MD Professor of Pediatrics and Medicine8,
  6. Peter G. Rose MD Head9 and
  7. Mikkael A. Sekeres MD, MS Director10
  1. Khaled Ali1,
  2. Ming Zhou2,
  3. Steve Campbell3,
  4. Ronald M. Bukowski1 and
  5. Brian I. Rini1

Published Online: 20 SEP 2012

DOI: 10.1002/9781118464557.ch1

Textbook of Uncommon Cancer

Textbook of Uncommon Cancer

How to Cite

Ali, K., Zhou, M., Campbell, S., Bukowski, R. M. and Rini, B. I. (2012) Uncommon Tumors of the Kidney, in Textbook of Uncommon Cancer (eds D. Raghavan, C. D. Blanke, D. H. Johnson, P. L. Moots, G. H. Reaman, P. G. Rose and M. A. Sekeres), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118464557.ch1

Editor Information

  1. 4

    Levine Cancer Institute, Carolinas HealthCare System; University of North Carolina School of Medicine, Charlotte, NC, USA

  2. 5

    Systemic Therapy, British Columbia Cancer Agency; Medical Oncology, University of British Columbia, Vancouver, BC, Canada

  3. 6

    Donald W. Seldin Distinguished Chair in Internal Medicine, Professor and Chairman, Department of Internal Medicine, The University of Texas Southwestern School of Medicine, Dallas, TX, USA

  4. 7

    Division of Neuro-Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center; Tennessee Valley Healthcare Systems, Veterans Administration Medical Center, Nashville, TN, USA

  5. 8

    The George Washington University School of Medicine and Health Sciences, Children's National Medical Center, Washington, DC, USA

  6. 9

    Section of Gynecologic Oncology, Cleveland Clinic Taussig Cancer Center; Professor of Medicine, Case Western Reserve University, Cleveland, OH, USA

  7. 10

    Leukemia Program, Associate Professor of Medicine, Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA

Author Information

  1. 1

    Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Institute, Glickman Urological Institute, Cleveland, OH, USA

  2. 2

    Department of Pathology

  3. 3

    Department of Urologic Oncology, Cleveland Clinic, Cleveland, OH, USA

Publication History

  1. Published Online: 20 SEP 2012
  2. Published Print: 22 FEB 2012

ISBN Information

Print ISBN: 9781118083734

Online ISBN: 9781118464557

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Keywords:

  • Angiomyolipoma;
  • Carcinoids;
  • collecting duct carcinomas;
  • Kidney cancer;
  • Lymphoma;
  • mucinous tubular and spindle cell carcinoma;
  • Oncocytoma;
  • Papillary adenoma;
  • Renal sarcomas;
  • Renal medullary carcinoma;
  • Wilms tumor;
  • XP11 translocation neoplasms

Summary

Tumors of the kidney account for about 3% of adult malignancies. About 60,920 new cases of kidney cancer (37,120 in men and 23,800 in women) were estimated by the American Cancer Society for the year 2011. Renal cell carcinomas constitute the bulk of these malignancies and historically they were widely known as hypernephroma, a term that was coined by Grawitz in the 19th century, reflecting his belief that they arose from the adrenal gland. Renal cell carcinomas are derived from the epithelial cells of renal tubules and account for more than 80% of primary renal malignant neoplasms. Transitional cell carcinomas, although arising in the renal pelvis, are frequently classified as renal tumors, and account for 7–8%. Other tumors, such as oncocytomas, collecting duct carcinomas of Bellini, and renal sarcomas, are uncommon but are becoming more frequently recognized pathologically. Nephroblastoma (Wilms tumor) is common in children and accounts for 5–6% of all primary renal tumors. This chapter focuses on the classification, pathology, genetics, clinical and radiographic manifestations, and surgical and systemic management of the less common malignant and benign tumors of the kidney.