66. Uncommon Pediatric Tumors of the Thorax

  1. Derek Raghavan MD, PhD, FACP, FRACP, FASCO President, Professor/Medicine3,
  2. Charles D. Blanke MD, FACP, FRCPC, FASCO Vice-President, Professor and Chief4,
  3. David H. Johnson MD5,
  4. Paul L. Moots MD Associate Professor of Neurology and Medicine, Chief6,
  5. Gregory H. Reaman MD Professor of Pediatrics and Medicine7,
  6. Peter G. Rose MD Head8 and
  7. Mikkael A. Sekeres MD, MS Director9
  1. Yoav H. Messinger1,
  2. Kris Ann P. Schultz1 and
  3. Louis P. Dehner2

Published Online: 20 SEP 2012

DOI: 10.1002/9781118464557.ch66

Textbook of Uncommon Cancer

Textbook of Uncommon Cancer

How to Cite

Messinger, Y. H., Schultz, K. A. P. and Dehner, L. P. (2012) Uncommon Pediatric Tumors of the Thorax, in Textbook of Uncommon Cancer (eds D. Raghavan, C. D. Blanke, D. H. Johnson, P. L. Moots, G. H. Reaman, P. G. Rose and M. A. Sekeres), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118464557.ch66

Editor Information

  1. 3

    Levine Cancer Institute, Carolinas HealthCare System; University of North Carolina School of Medicine, Charlotte, NC, USA

  2. 4

    Systemic Therapy, British Columbia Cancer Agency; Medical Oncology, University of British Columbia, Vancouver, BC, Canada

  3. 5

    Donald W. Seldin Distinguished Chair in Internal Medicine, Professor and Chairman, Department of Internal Medicine, The University of Texas Southwestern School of Medicine, Dallas, TX, USA

  4. 6

    Division of Neuro-Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center; Tennessee Valley Healthcare Systems, Veterans Administration Medical Center, Nashville, TN, USA

  5. 7

    The George Washington University School of Medicine and Health Sciences, Children's National Medical Center, Washington, DC, USA

  6. 8

    Section of Gynecologic Oncology, Cleveland Clinic Taussig Cancer Center; Professor of Medicine, Case Western Reserve University, Cleveland, OH, USA

  7. 9

    Leukemia Program, Associate Professor of Medicine, Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA

Author Information

  1. 1

    Department of Pediatric Hematology/Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, USA

  2. 2

    Lauren V. Ackerman Department of Surgical Pathology, Barnes-Jewish Hospital; Department of Pathology and Immunology, St Louis Children's Hospital, Washington University Medical Center, St Louis, MO, USA

Publication History

  1. Published Online: 20 SEP 2012
  2. Published Print: 22 FEB 2012

ISBN Information

Print ISBN: 9781118083734

Online ISBN: 9781118464557



  • Chest wall;
  • FLIT;
  • GCN;
  • IMT;
  • Lung and airways;
  • Mediastinum;
  • NET;
  • Neurogenic neoplasms;
  • PPB;
  • Thorax


Although common in the adult population, primary pulmonary malignancies in the age group less than 20 years at diagnosis are quite rare. The most common malignant pulmonary neoplasms in children are, in fact, metastases from other primary tumors, primarily sarcomas. The purpose of this chapter is to discuss a group of neoplasms of diverse pathological types, which have in common their origin from intrathoracic organs or structures or the chest wall, and have been described in children. Most of these neoplasms are malignant, including lymphomas and neuroblastic tumors, although the clinical behavior is dependent upon the specific tumor type and the pathological stage. Several of the tumor types are diagnosed almost exclusively in children, especially the pleuropulmonary blastoma which is the most common primary malignancy of the lung in children.