18. Sexual Dysfunction in Long-Term Survivors: Monitoring and Management

  1. Bipin N Savani MD
  1. Andrea L Utz and
  2. Shubhada Jagasia

Published Online: 6 SEP 2013

DOI: 10.1002/9781118473306.ch18

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

How to Cite

Utz, A. L. and Jagasia, S. (2013) Sexual Dysfunction in Long-Term Survivors: Monitoring and Management, in Blood and Marrow Transplantation Long-Term Management: Prevention and Complications (ed B. N. Savani), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118473306.ch18

Editor Information

  1. Professor of Medicine,Director, Long Term Transplant Clinic, Hematology and Stem Cell Transplantation Section, Vanderbilt University Medical Center, Nashville, TN, USA

Author Information

  1. Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA

Publication History

  1. Published Online: 6 SEP 2013
  2. Published Print: 1 OCT 2013

ISBN Information

Print ISBN: 9781118473405

Online ISBN: 9781118473306

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Keywords:

  • hypogonadism;
  • testosterone;
  • infertility;
  • azoospermia;
  • stem cell transplant;
  • erectile dysfunction;
  • sexual function

Summary

Sexual dysfunction is common following stem cell transplantation due to hormonal, anatomic, and psychological alterations. Gonadal toxicity, primarily induced by alkylating chemotherapeutics and radiation, frequently leads to decreased sperm production and can cause decreased testosterone levels. Pretreatment sperm storage should be considered when possible, and appropriate assessment and replacement of testosterone deficiency may improve libido, erectile dysfunction, bone density, muscle mass, and energy in this population. Evaluating and treating psychological and medical issues affecting sexual function likely improves long-term quality of life.