21. Posttransplant Diabetes Mellitus: Monitoring, Prevention, and Management Guidelines

  1. Bipin N Savani MD
  1. Prathima Jasti,
  2. Shichun Bao and
  3. Shubhada Jagasia

Published Online: 6 SEP 2013

DOI: 10.1002/9781118473306.ch21

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

How to Cite

Jasti, P., Bao, S. and Jagasia, S. (2013) Posttransplant Diabetes Mellitus: Monitoring, Prevention, and Management Guidelines, in Blood and Marrow Transplantation Long-Term Management: Prevention and Complications (ed B. N. Savani), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118473306.ch21

Editor Information

  1. Professor of Medicine,Director, Long Term Transplant Clinic, Hematology and Stem Cell Transplantation Section, Vanderbilt University Medical Center, Nashville, TN, USA

Author Information

  1. Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Publication History

  1. Published Online: 6 SEP 2013
  2. Published Print: 1 OCT 2013

ISBN Information

Print ISBN: 9781118473405

Online ISBN: 9781118473306

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Keywords:

  • stem cell transplant;
  • posttransplant diabetes;
  • prednisone;
  • tacrolimus;
  • impaired glucose tolerance

Summary

With advances in the science of transplantation, there has been a significant rise in the frequency of hematopoietic stem cell transplants for a variety of indications. Improved supportive care strategies have led to an increase in the number of long-term survivors and thereby increased prevalence of chronic health conditions like diabetes, dyslipidemia, impaired glucose tolerance, hypertension, and metabolic syndrome, all of which predispose to cardiovascular events. Diabetes is a major long-term morbidity associated with transplantation. This chapter focuses on the prevalence, pathogenesis, prevention, diagnosis, and management strategies of post-stem-cell transplant diabetes.