23. Special Issues Related to Female Long-Term Survivors

  1. Bipin N Savani MD
  1. Melissa A Merideth1,
  2. Kristin Clay Chabarria3,
  3. Tajana Klepac Pulanic4 and
  4. Pamela Stratton4

Published Online: 6 SEP 2013

DOI: 10.1002/9781118473306.ch23

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

How to Cite

Merideth, M. A., Chabarria, K. C., Pulanic, T. K. and Stratton, P. (2013) Special Issues Related to Female Long-Term Survivors, in Blood and Marrow Transplantation Long-Term Management: Prevention and Complications (ed B. N. Savani), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118473306.ch23

Editor Information

  1. Professor of Medicine,Director, Long Term Transplant Clinic, Hematology and Stem Cell Transplantation Section, Vanderbilt University Medical Center, Nashville, TN, USA

Author Information

  1. 1

    Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA

  2. 3

    University of Zagreb School of Medicine, Zagreb, Croatia

  3. 4

    Community Health Center East, Zagreb, Croatia

Publication History

  1. Published Online: 6 SEP 2013
  2. Published Print: 1 OCT 2013

ISBN Information

Print ISBN: 9781118473405

Online ISBN: 9781118473306

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Keywords:

  • genital graft-versus-host disease (GVHD);
  • human papillomavirus (HPV);
  • ovarian failure;
  • female sexual dysfunction;
  • infertility;
  • cervical cancer;
  • cervical cytology

Summary

Female survivors after hematopoietic stem cell transplantation face gynecologic issues that can significantly impact quality of life in long-term survivors. These issues include genital graft-versus-host disease, genital human papillomavirus-associated infection, dysplasia and cancer, transient or permanent ovarian failure, infertility, and sexual dysfunction. The incidence, pathogenesis, clinical evaluation, and management of these gynecologic issues are presented. A detailed approach to gynecologic care as outlined in this chapter may ameliorate many of these issues and potentially help to improve sexual health, and thus overall quality of life, for female long-term survivors.