35. Health-Related Quality of Life in Adult and Pediatric Survivors of Hematopoietic Stem Cell Transplantation

  1. Bipin N Savani MD
  1. Margaret Bevans1 and
  2. Lori Wiener2

Published Online: 6 SEP 2013

DOI: 10.1002/9781118473306.ch35

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

How to Cite

Bevans, M. and Wiener, L. (2013) Health-Related Quality of Life in Adult and Pediatric Survivors of Hematopoietic Stem Cell Transplantation, in Blood and Marrow Transplantation Long-Term Management: Prevention and Complications (ed B. N. Savani), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118473306.ch35

Editor Information

  1. Professor of Medicine,Director, Long Term Transplant Clinic, Hematology and Stem Cell Transplantation Section, Vanderbilt University Medical Center, Nashville, TN, USA

Author Information

  1. 1

    LCDR, United States Public Health Service, National Institutes of Health, Clinical Center, Bethesda, MD, USA

  2. 2

    Psychosocial Support and Research Program, Center for Cancer Research, Pediatric Oncology Branch, NIH, Bethesda, MD, USA

Publication History

  1. Published Online: 6 SEP 2013
  2. Published Print: 1 OCT 2013

ISBN Information

Print ISBN: 9781118473405

Online ISBN: 9781118473306

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Keywords:

  • quality of life;
  • survivors;
  • psychosocial;
  • patient-reported outcomes;
  • pediatric survivors;
  • adult survivors;
  • function;
  • psychological;
  • role;
  • lifestyle behaviors

Summary

Hematopoietic stem cell transplantation (HSCT) has seen considerable progress in the past 50 years; and as the number of survivors continues to grow, heath-related quality of life (HRQL), including psychosocial effects, has become a priority in this population. Survivors may experience impairments for many years following HSCT and despite the evidence that HRQL may also be compromised; the translation of this knowledge into practice remains limited. This chapter defines HRQL and highlights areas of potential impact for the patient and family throughout the course of treatment and beyond for both pediatric and adult patients and their family members. As some specific differences have been found in factors affecting HRQL in adult and pediatric patients, the chapter will separate the age groups for purposes of clarity. Positive outcomes along with ongoing challenges are discussed. Suggested screening, assessment, and interventions to improve care are offered.