6. Graft-Versus-Host Disease and Late Effects After Hematopoetic Stem Cell Transplantation

  1. Bipin N Savani MD
  1. Gérard Socié

Published Online: 6 SEP 2013

DOI: 10.1002/9781118473306.ch6

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

Blood and Marrow Transplantation Long-Term Management: Prevention and Complications

How to Cite

Socié, G. (2013) Graft-Versus-Host Disease and Late Effects After Hematopoetic Stem Cell Transplantation, in Blood and Marrow Transplantation Long-Term Management: Prevention and Complications (ed B. N. Savani), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118473306.ch6

Editor Information

  1. Professor of Medicine,Director, Long Term Transplant Clinic, Hematology and Stem Cell Transplantation Section, Vanderbilt University Medical Center, Nashville, TN, USA

Author Information

  1. University Paris VII, Haematology/Transplantation, Hôpital Saint Louis, Paris, France

Publication History

  1. Published Online: 6 SEP 2013
  2. Published Print: 1 OCT 2013

ISBN Information

Print ISBN: 9781118473405

Online ISBN: 9781118473306

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Keywords:

  • chronic GVHD;
  • immune deficiency;
  • multistep carcinogenesis

Summary

Chronic graft-versus-host disease and the associated immunodeficiency are the primary causes of transplant-related mortality late after allogeneic stem cell transplantation and contribute directly or indirectly to most late complications. The main concepts are reviewed in two different sections: nonmalignant late effects and secondary malignant diseases