61. Hypertrophic Cardiomyopathy: Risk Stratification and Management of Arrhythmia

  1. Mohammad Shenasa MD2,
  2. Gerhard Hindricks MD3,
  3. Martin Borggrefe MD4,
  4. Günter Breithardt MD5 and
  5. Mark E. Josephson MD6
  1. Pier D. Lambiase and
  2. William J. McKenna

Published Online: 18 DEC 2012

DOI: 10.1002/9781118481585.ch61

Cardiac Mapping, Fourth Edition

Cardiac Mapping, Fourth Edition

How to Cite

Lambiase, P. D. and McKenna, W. J. (2013) Hypertrophic Cardiomyopathy: Risk Stratification and Management of Arrhythmia, in Cardiac Mapping, Fourth Edition (eds M. Shenasa, G. Hindricks, M. Borggrefe, G. Breithardt and M. E. Josephson), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118481585.ch61

Editor Information

  1. 2

    Attending Physician, Department of Cardiovascular Services, O'Connor Hospital, Heart & Rhythm Medical Group, San Jose, California, USA

  2. 3

    Professor of Medicine (Cardiology), University Leipzig, Heart Center, Director, Department of Electrophysiology, Leipzig, Germany

  3. 4

    Professor of Medicine (Cardiology), Head, Department of Cardiology, Angiology and Pneumology, University Medical Center, Mannheim Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

  4. 5

    Professor Emeritus of Medicine and Cardiology, Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany

  5. 6

    Chief, Cardiovascular Medicine Division, Director, Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Herman C. Dana Professor of Medicine, Harvard Medical School, Boston, Massachusetts, USA

Author Information

  1. Institute of Cardiovascular Science, University College London, London, UK

Publication History

  1. Published Online: 18 DEC 2012
  2. Published Print: 10 JAN 2013

ISBN Information

Print ISBN: 9780470670460

Online ISBN: 9781118481585



  • hypertrophic cardiomyopathy;
  • ablation;
  • sudden death;
  • risk;
  • atrial fibrillation;
  • ventricular arrhythmia


Hypertrophic cardiomyopathy (HCM) is a common condition affecting 1 in 500 of the population. An electrophysiologist is most likely to become involved with such patients in the investigation and management syncope, risk stratification to implant an internal cardiac defibrillator (ICD) and the management of arrhythmias in this condition. This chapter focuses on mechanisms of ventricular arrhythmia in HCM, risk stratification and the ablation of atrial and ventricular arrhythmias considering the role of cardiac imaging modalities in these scenarios. Finally implantation of pacemakers and ICDs is discussed with special attention to HCM-specific issues.