62. Role of Magnetic Resonance Imaging in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

  1. Mohammad Shenasa MD2,
  2. Gerhard Hindricks MD3,
  3. Martin Borggrefe MD4,
  4. Günter Breithardt MD5 and
  5. Mark E. Josephson MD6
  1. Aditya Bhonsale,
  2. Hugh Calkins and
  3. Harikrishna Tandri

Published Online: 18 DEC 2012

DOI: 10.1002/9781118481585.ch62

Cardiac Mapping, Fourth Edition

Cardiac Mapping, Fourth Edition

How to Cite

Bhonsale, A., Calkins, H. and Tandri, H. (2013) Role of Magnetic Resonance Imaging in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, in Cardiac Mapping, Fourth Edition (eds M. Shenasa, G. Hindricks, M. Borggrefe, G. Breithardt and M. E. Josephson), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118481585.ch62

Editor Information

  1. 2

    Attending Physician, Department of Cardiovascular Services, O'Connor Hospital, Heart & Rhythm Medical Group, San Jose, California, USA

  2. 3

    Professor of Medicine (Cardiology), University Leipzig, Heart Center, Director, Department of Electrophysiology, Leipzig, Germany

  3. 4

    Professor of Medicine (Cardiology), Head, Department of Cardiology, Angiology and Pneumology, University Medical Center, Mannheim Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

  4. 5

    Professor Emeritus of Medicine and Cardiology, Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany

  5. 6

    Chief, Cardiovascular Medicine Division, Director, Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Herman C. Dana Professor of Medicine, Harvard Medical School, Boston, Massachusetts, USA

Author Information

  1. The Johns Hopkins Hospital, Baltimore, MD, USA

Publication History

  1. Published Online: 18 DEC 2012
  2. Published Print: 10 JAN 2013

ISBN Information

Print ISBN: 9780470670460

Online ISBN: 9781118481585

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Keywords:

  • MRI imaging protocol for ARVD/C;
  • MRI structural abnormalities in ARVD/C;
  • MRI functional abnormalities in ARVD/C;
  • delayed enhancement of RV;
  • LV involvement in ARVD/C;
  • role of MRI in diagnosis of ARVD/C;
  • role of MRI in catheter ablation of VT in patients with ARVD/C

Summary

Accurate and reliable evaluation of the right ventricle (RV) is desirable both for establishing the diagnosis and for follow up evaluation of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). The non-invasive nature of magnetic resonance imaging (MRI), multiplanar capability, and unique ability to provide tissue characterization are ideal for assessment of RV structure and functional alterations in ARVD/C. Morphologic abnormalities on MRI include intramyocardial fat deposits, focal fibrosis, wall thinning, wall hypertrophy, trabecular disarray, and RV outflow tract enlargement. The introduction of quantitative MRI cut-offs for global RV volumes and function have refined the diagnosis of ARVD/C. Regional functional abnormalities of the RV described in ARVD/C include focal hypokinesis (wall thickening of <40%), akinesis (systolic wall thickening of <10%), dyskinesis (myocardial segment, which moves outward in systole) and aneurysms (segments with persistent bulging in diastole, and dyskinetic in systole). Serial quantitative volumetric assessment of RV may play an important in assessing RV function in first-degree relatives.