10. Towards High-Throughput Cell Mechanics Assays for Research and Clinical Applications

  1. Horacio D. Espinosa4 and
  2. Gang Bao5
  1. David R. Myers1,2,
  2. Daniel A. Fletcher3 and
  3. Wilbur A. Lam1,2

Published Online: 11 DEC 2012

DOI: 10.1002/9781118482568.ch10

Nano and Cell Mechanics: Fundamentals and Frontiers

Nano and Cell Mechanics: Fundamentals and Frontiers

How to Cite

Myers, D. R., Fletcher, D. A. and Lam, W. A. (2013) Towards High-Throughput Cell Mechanics Assays for Research and Clinical Applications, in Nano and Cell Mechanics: Fundamentals and Frontiers (eds H. D. Espinosa and G. Bao), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118482568.ch10

Editor Information

  1. 4

    Northwestern University, USA

  2. 5

    Georgia Institute of Technology, USA

Author Information

  1. 1

    Aflac Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta and Emory University School of Medicine, USA

  2. 2

    Georgia Institute of Technology and Emory University, USA

  3. 3

    University of California at Berkeley, USA

Publication History

  1. Published Online: 11 DEC 2012
  2. Published Print: 10 JAN 2013

ISBN Information

Print ISBN: 9781118460399

Online ISBN: 9781118482568

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Keywords:

  • hematolog;
  • blood cells;
  • cell mechanics;
  • high-throughput;
  • clinical assay;
  • microfluidics;
  • flow chambers;
  • optical tweezers;
  • atomic force microscopy;
  • micropipette aspiration;
  • microfiltration;
  • rheometry;
  • ektacytometry;
  • cell deformation

Summary

This chapter contains sections titled:

  • Cell Mechanics Overview

  • Bulk Assays

  • Single-Cell Techniques

  • Existing High-Throughput Cell Mechanical-Based Assays

  • Cell Mechanical Properties and Diseases

  • References