9. Engineering Nano-Probes for Live-Cell Imaging of Gene Expression

  1. Horacio D. Espinosa3 and
  2. Gang Bao4
  1. Gang Bao4,
  2. Brian Wile1 and
  3. Andrew Tsourkas2

Published Online: 11 DEC 2012

DOI: 10.1002/9781118482568.ch9

Nano and Cell Mechanics: Fundamentals and Frontiers

Nano and Cell Mechanics: Fundamentals and Frontiers

How to Cite

Bao, G., Wile, B. and Tsourkas, A. (2013) Engineering Nano-Probes for Live-Cell Imaging of Gene Expression, in Nano and Cell Mechanics: Fundamentals and Frontiers (eds H. D. Espinosa and G. Bao), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118482568.ch9

Editor Information

  1. 3

    Northwestern University, USA

  2. 4

    Georgia Institute of Technology, USA

Author Information

  1. 1

    Department of Biomedical Engineering, Georgia Institute of Technology and Emory, USA

  2. 2

    Department of Bioengineering, University of Pennsylvania, USA

  3. 4

    Georgia Institute of Technology, USA

Publication History

  1. Published Online: 11 DEC 2012
  2. Published Print: 10 JAN 2013

ISBN Information

Print ISBN: 9781118460399

Online ISBN: 9781118482568

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Keywords:

  • live-cell imaging;
  • probes;
  • fluorescent linear probes;
  • linear FRET probes;
  • auto-ligation;
  • biological;
  • molecular beacon delivery;
  • engineering challenges

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular Probes for RNA Detection

  • Probe Design, Imaging, and Biological Issues

  • Delivery of Molecular Beacons

  • Engineering Challenges and Future Directions

  • Acknowledgments

  • References