3. Living-Donor Liver Transplantation

  1. Nizam Mamode2 and
  2. Raja Kandaswamy3
  1. Abhideep Chaudhary and
  2. Abhinav Humar

Published Online: 23 DEC 2012

DOI: 10.1002/9781118483664.ch3

Abdominal Organ Transplantation: State of the Art

Abdominal Organ Transplantation: State of the Art

How to Cite

Chaudhary, A. and Humar, A. (2013) Living-Donor Liver Transplantation, in Abdominal Organ Transplantation: State of the Art (eds N. Mamode and R. Kandaswamy), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118483664.ch3

Editor Information

  1. 2

    Guy's and St Thomas' Hospital, Great Ormond Street Hospital, London, UK

  2. 3

    Department of Surgery, University of Minnesota, Minneapolis, MN, USA

Author Information

  1. Department of Surgery, University of Pittsburgh, Medical Center (UPMC), USA

Publication History

  1. Published Online: 23 DEC 2012
  2. Published Print: 12 FEB 2013

ISBN Information

Print ISBN: 9781444334326

Online ISBN: 9781118483664

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Keywords:

  • Living donor liver transplant;
  • Liver transplant;
  • Living donor;
  • Donor Evaluation;
  • Right hepatectomy;
  • Left hepatectomy;
  • Left lateral hepatectomy;
  • Donor Morbidity;
  • Donor Mortality;
  • Small for Size;
  • Biliary complications

Summary

The scarcity of donor organs is the major limiting factor in liver transplantation. Living donor liver transplant (LDLT) has evolved over last two decades as an alternative to deceased donor transplant in the western world. The primary concern with the development of LDLT remains the potential for mortality and morbidity in the healthy donor. While there is no obvious benefit for the donor, there are survival advantages for recipients of LDLT. Most notable is that waiting times can be reduced, allowing the transplant to be performed before the recipient's health deteriorates. In areas of the world where deceased donor transplants are not performed due to nonexistent deceased donor graft donation, the advantages of LDLT are even more obvious. Despite being technically complex and labor intensive, LDLT has continued to evolve in the recent years leading to increased donor safety and better short term recipient outcomes. But, long term results, both in donor as well as the recipient, need to be better defined.