6. Allotransplantation of Pancreatic Islets
- Nizam Mamode4,
- Raja Kandaswamy5
Published Online: 23 DEC 2012
DOI: 10.1002/9781118483664.ch6
Copyright © 2013 Blackwell Publishing Ltd.
Book Title
Abdominal Organ Transplantation: State of the Art
Additional Information
How to Cite
Juszczak, M. T. and Johnson, P. R. V. (2013) Allotransplantation of Pancreatic Islets, in Abdominal Organ Transplantation: State of the Art (eds N. Mamode and R. Kandaswamy), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118483664.ch6
Editor Information
- 4
Guy's and St Thomas' Hospital, Great Ormond Street Hospital, London, UK
- 5
Department of Surgery, University of Minnesota, Minneapolis, MN, USA
Publication History
- Published Online: 23 DEC 2012
- Published Print: 12 FEB 2013
ISBN Information
Print ISBN: 9781444334326
Online ISBN: 9781118483664
- Summary
- Chapter
- References
Keywords:
- islet transplantation;
- pancreas;
- islet cell;
- allotransplantation;
- type-1 diabetes mellitus;
- T1DM;
- immunosuppression
Summary
SLET transplantation has become a recognised treatment for brittle Type 1 Diabetes Mellitus. Indeed, the short and mid-term results for this treatment are now equivalent to those achieved with vascularised pancreas transplants. It is therefore important for the transplant clinician to be familiar with the different aspects of this therapy. This chapter provides an overall summary of islet transplantation, including donor selection, islet isolation, recipient selection and work-up, the transplant itself, and the post-operative management and outcomes.