9. Pediatric Renal Transplantation

  1. Nizam Mamode2 and
  2. Raja Kandaswamy3
  1. Stephen D. Marks

Published Online: 23 DEC 2012

DOI: 10.1002/9781118483664.ch9

Abdominal Organ Transplantation: State of the Art

Abdominal Organ Transplantation: State of the Art

How to Cite

Marks, S. D. (2013) Pediatric Renal Transplantation, in Abdominal Organ Transplantation: State of the Art (eds N. Mamode and R. Kandaswamy), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118483664.ch9

Editor Information

  1. 2

    Guy's and St Thomas' Hospital, Great Ormond Street Hospital, London, UK

  2. 3

    Department of Surgery, University of Minnesota, Minneapolis, MN, USA

Author Information

  1. Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK

Publication History

  1. Published Online: 23 DEC 2012
  2. Published Print: 12 FEB 2013

ISBN Information

Print ISBN: 9781444334326

Online ISBN: 9781118483664



  • children;
  • adolescents;
  • end-stage renal failure;
  • transplantation;
  • management;
  • complications;
  • outcomes


Paediatric end-stage renal failure programmes have evolved over the last twenty-five years with the provision of dialysis and transplantation. There have been advances in the treatment of renal conditions in children to prevent progression of renal failure. However, many children with end-stage renal failure can have excellent quality of life despite multi-system diseases and dialysis can now be offered as a bridge to transplantation to anuric neonates who would otherwise not have survived. The current gold standard treatment for children in end-stage renal failure is pre-emptive living related renal transplantation and advances in patient management including modern immunosuppressive regimens have improved the long term patient and renal allograft survival. Children with ESRF can now have increased quantity and quality of life with the benefits of transplantation and increased possibilities of re-transplantation in the future.