10. Melanoma

  1. A. Neil Crowson MD1,
  2. Cynthia M. Magro MD2 and
  3. Martin C. Mihm JR. MD3

Published Online: 17 JAN 2014

DOI: 10.1002/9781118488935.ch10

The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions, Second Edition

The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions, Second Edition

How to Cite

Crowson, A. N., Magro, C. M. and Mihm, M. C. (eds) (2014) Melanoma, in The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118488935.ch10

Editor Information

  1. 1

    Clinical Professor of Dermatology, Pathology and Surgery; Director of Dermatopathology, University of Oklahoma; President, Pathology Laboratory Associates; Chief of Staff, St. John Medical Center, Tulsa, OK, USA

  2. 2

    Professor of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY, USA

  3. 3

    Clinical Professor, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Co-Director, Melanoma Programme, European Organisation for the Research and Treatment of Cancer, Brussels, Belgium

Publication History

  1. Published Online: 17 JAN 2014
  2. Published Print: 21 MAR 2014

ISBN Information

Print ISBN: 9780470561553

Online ISBN: 9781118488935

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Keywords:

  • lentiginous melanoma;
  • prognostication;
  • tumor thickness;
  • vertical growth phase

Summary

This chapter presents a comprehensive summary of the basic criteria that are critical to the histologic diagnosis of melanoma. It focuses on the clinical features of the prototypic subgroups of melanoma such as lentiginous melanoma. After a consideration of the clinical features, the histology of the radial growth phase as it relates to specific subtypes of melanoma is addressed followed by a discussion on the recognition of the vertical growth phase. Five-year survival rates according to measured Breslow thickness are given in the chapter for patients with stage I lesions, where the tumor is confined to the primary site of the melanoma without regional lymph node involvement or distant metastatic disease. Unusual forms of melanoma are discussed at the end of the chapter.