20. Appendix A: Statistics

  1. Ingvar Eidhammer,
  2. Harald Barsnes,
  3. Geir Egil Eide and
  4. Lennart Martens

Published Online: 10 JAN 2013

DOI: 10.1002/9781118494042.ch20

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

How to Cite

Eidhammer, I., Barsnes, H., Eide, G. E. and Martens, L. (2013) Appendix A: Statistics, in Computational and Statistical Methods for Protein Quantification by Mass Spectrometry, John Wiley & Sons Ltd, Oxford, UK. doi: 10.1002/9781118494042.ch20

Publication History

  1. Published Online: 10 JAN 2013
  2. Published Print: 4 JAN 2013

ISBN Information

Print ISBN: 9781119964001

Online ISBN: 9781118494042

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Keywords:

  • hypothesis testing;
  • protein quantification;
  • statistical populations;
  • statistics;
  • variance

Summary

Statistics is an important part of protein quantification projects. This appendix section describes the essential parts of statistics related to quantification projects. It provides a brief explanation of the most used concepts in a compact and unified way. Statistics can be defined as a scientific field consisting of four subfields: collection of data; analysis of data; interpretation or explanation of data; and presentation of data. The data analyzed in quantitative protein projects usually constitute samples from statistical populations. The appendix presents hypothesis testing and types of errors that occur while performing the hypothesis testing. When presenting the statistics used it is common to distinguish between the case where there are exactly two populations in the analysis, and the case where there are more than two. The appendix shows that for small normally distributed populations the statistics used for comparing means depend on the variances being equal or different.

Controlled Vocabulary Terms

hypothesis testing; variance