7. Immunogenicity Versus Immunomodulation of Perinatal Stem Cells

  1. Kyle J. Cetrulo3,
  2. Curtis L. Cetrulo Jr.4 and
  3. Rouzbeh R. Taghizadeh3
  1. Bram Lutton1 and
  2. Raimon Duran-Struuck2

Published Online: 19 FEB 2013

DOI: 10.1002/9781118497883.ch7

Perinatal Stem Cells, Second Edition

Perinatal Stem Cells, Second Edition

How to Cite

Lutton, B. and Duran-Struuck, R. (2013) Immunogenicity Versus Immunomodulation of Perinatal Stem Cells, in Perinatal Stem Cells, Second Edition (eds K. J. Cetrulo, C. L. Cetrulo and R. R. Taghizadeh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118497883.ch7

Editor Information

  1. 3

    AuxoCell Laboratories, Inc., Cambridge, MA, USA

  2. 4

    Division of Plastic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

Author Information

  1. 1

    Endicott College, Beverly, MA, USA

  2. 2

    Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Publication History

  1. Published Online: 19 FEB 2013
  2. Published Print: 8 MAR 2013

ISBN Information

Print ISBN: 9781118209448

Online ISBN: 9781118497883

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Keywords:

  • immunogenicity/immunomodulation;
  • perinatal stem cells;
  • umbilical, bone marrow-derived MSCs;
  • immunomodulation mechanisms;
  • host responses, Yin and Yang

Summary

This chapter contains sections titled:

  • Introduction

  • Mechanisms of Immunomodulation by Umbilical Cord- and Bone Marrow-Derived MSCs

  • Innate Immune System

  • Adaptive Immune System

  • Natural Tolerance and Umbilical Cord Tissues

  • Tolerance versus Immunogenicity: The Yin and Yang of Host Responses to Umbilical Cord-Derived Cells

  • Conclusions

  • References