11. Imaging Mass Spectrometry for Drugs and Metabolites

  1. Walter A. Korfmacher
  1. Stacey R. Oppenheimer

Published Online: 17 JAN 2013

DOI: 10.1002/9781118516157.ch11

Mass Spectrometry for Drug Discovery and Drug Development

Mass Spectrometry for Drug Discovery and Drug Development

How to Cite

Oppenheimer, S. R. (2013) Imaging Mass Spectrometry for Drugs and Metabolites, in Mass Spectrometry for Drug Discovery and Drug Development (ed W. A. Korfmacher), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118516157.ch11

Editor Information

  1. Genzyme, a SANOFI Company, Waltham, MA, USA

Author Information

  1. Pfizer, Groton, CT, USA

Publication History

  1. Published Online: 17 JAN 2013
  2. Published Print: 22 JAN 2013

Book Series:

  1. Wiley Series on Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio3 and
  2. Nico M. M. Nibbering4

Series Editor Information

  1. 3

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 4

    Vrije Universiteit Amsterdam, The Netherlands

ISBN Information

Print ISBN: 9780470942383

Online ISBN: 9781118516157

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Keywords:

  • IMS in drug/metabolite distribution;
  • MS in pharmaceutical/R&D, for newer medicines;
  • MS-based imaging in spatial, SIMS/DESI;
  • MSI in drug distribution;
  • MALDI imaging, complementary to QWBA

Summary

This chapter contains sections titled:

  • Introduction

  • Conventional Imaging Technologies

  • Mass Spectrometry Imaging (MSI) Technologies for Drug Distribution

  • Fundamentals of Imaging MS

  • Applications of Imaging MS to Drug and Metabolite Imaging

  • Future Advancements

  • Conclusions

  • References