6. MS Analysis of Biological Drugs, Proteins, and Peptides

  1. Walter A. Korfmacher
  1. Yi Du1,
  2. John Mehl2 and
  3. Pavlo Pristatsky3

Published Online: 17 JAN 2013

DOI: 10.1002/9781118516157.ch6

Mass Spectrometry for Drug Discovery and Drug Development

Mass Spectrometry for Drug Discovery and Drug Development

How to Cite

Du, Y., Mehl, J. and Pristatsky, P. (2013) MS Analysis of Biological Drugs, Proteins, and Peptides, in Mass Spectrometry for Drug Discovery and Drug Development (ed W. A. Korfmacher), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118516157.ch6

Editor Information

  1. Genzyme, a SANOFI Company, Waltham, MA, USA

Author Information

  1. 1

    WuXi AppTec Co., Ltd., Shanghai, China

  2. 2

    Bioanalytical Research, Bristol-Myers Squibb, Princeton, NJ, USA

  3. 3

    Merck & Co., West Point, PA, USA

Publication History

  1. Published Online: 17 JAN 2013
  2. Published Print: 22 JAN 2013

Book Series:

  1. Wiley Series on Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio5 and
  2. Nico M. M. Nibbering6

Series Editor Information

  1. 5

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 6

    Vrije Universiteit Amsterdam, The Netherlands

ISBN Information

Print ISBN: 9780470942383

Online ISBN: 9781118516157

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Keywords:

  • MS of biological drugs/proteins/peptides;
  • MS in protein drug discovery/development;
  • biological drug discovery, MS applications;
  • structural characterization;
  • therapeutics, and full protein characterization

Summary

This chapter contains sections titled:

  • Introduction

  • Primary Sequence Characterization

  • Structural Characterization

  • Future Development

  • Summary

  • Acknowledgments

  • References