11. Natural Fibrous Proteins: Structural Analysis, Assembly, and Applications

  1. Juan M. Ruso and
  2. Ángel Piñeiro
  1. Mark J. van Raaij and
  2. Anna Mitraki

Published Online: 5 MAR 2013

DOI: 10.1002/9781118523063.ch11

Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science

Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science

How to Cite

van Raaij, M. J. and Mitraki, A. (2013) Natural Fibrous Proteins: Structural Analysis, Assembly, and Applications, in Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science (eds J. M. Ruso and Á. Piñeiro), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118523063.ch11

Author Information

  1. Departamento de Estructura de Macromoléculas, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.

Publication History

  1. Published Online: 5 MAR 2013
  2. Published Print: 18 FEB 2013

ISBN Information

Print ISBN: 9780470952511

Online ISBN: 9781118523063

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Keywords:

  • biotechnology;
  • materials science;
  • natural fibrous proteins;
  • protein assembly;
  • structural analysis

Summary

This chapter provides an overview of natural fibrous proteins, their function, structure, and assembly (naturally, in disease and in the laboratory). It reviews efforts in using fibrous proteins in biotechnology and materials science. The fibrous proteins discussed are intracellular fibrous proteins, extracellular fibrous proteins, virus and bacteriophage fibers, and amyloid-type fibrous proteins and silk. It talks about alpha-helical structures, structures containing beta-pleated sheets, and collagen fold. The repetitive building blocks of the natural fibrous proteins described in this chapter provide useful models for the design of artificial fibrous polymers. Fibrous structural motifs can serve as rich sources of inspiration for the design and engineering of novel biomaterials.