12. The Control of RNA Interference with Light

  1. Kun Cheng2 and
  2. Ram I. Mahato3
  1. Simon H. Friedman

Published Online: 26 APR 2013

DOI: 10.1002/9781118610749.ch12

Advanced Delivery and Therapeutic Applications of RNAi

Advanced Delivery and Therapeutic Applications of RNAi

How to Cite

Friedman, S. H. (2013) The Control of RNA Interference with Light, in Advanced Delivery and Therapeutic Applications of RNAi (eds K. Cheng and R. I. Mahato), John Wiley and Sons, Ltd, Chichester, UK. doi: 10.1002/9781118610749.ch12

Editor Information

  1. 2

    School of Pharmacy, University of Missouri-Kansas City, USA

  2. 3

    Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, USA

Author Information

  1. Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, USA

Publication History

  1. Published Online: 26 APR 2013
  2. Published Print: 10 JUN 2013

ISBN Information

Print ISBN: 9781119976868

Online ISBN: 9781118610749

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Keywords:

  • RNA interference;
  • siRNA;
  • dsRNA;
  • light activation

Summary

RNA interference is a ubiquitous mechanism of gene-expression regulation. By bringing this process under the control of light, the spacing, timing and degree of gene expression can be controlled. In this chapter we explore the variety of ways in which RNA Interference has been brought under the control of light.