15. RNAi in Liver Diseases

  1. Kun Cheng2 and
  2. Ram I. Mahato3
  1. Jiang Li,
  2. Jianqin Lu,
  3. Yifei Zhang,
  4. Mohammed Ghazwani,
  5. Peng Zhang,
  6. Xiang Gao and
  7. Song Li

Published Online: 26 APR 2013

DOI: 10.1002/9781118610749.ch15

Advanced Delivery and Therapeutic Applications of RNAi

Advanced Delivery and Therapeutic Applications of RNAi

How to Cite

Li, J., Lu, J., Zhang, Y., Ghazwani, M., Zhang, P., Gao, X. and Li, S. (2013) RNAi in Liver Diseases, in Advanced Delivery and Therapeutic Applications of RNAi (eds K. Cheng and R. I. Mahato), John Wiley and Sons, Ltd, Chichester, UK. doi: 10.1002/9781118610749.ch15

Editor Information

  1. 2

    School of Pharmacy, University of Missouri-Kansas City, USA

  2. 3

    Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, USA

Author Information

  1. Center for Pharmacogenetics, Department of Pharmaceutical Sciences University of Pittsburgh School of Pharmacy USA

Publication History

  1. Published Online: 26 APR 2013
  2. Published Print: 10 JUN 2013

ISBN Information

Print ISBN: 9781119976868

Online ISBN: 9781118610749

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Keywords:

  • HBV;
  • HCV;
  • HCC;
  • liver fibrosis;
  • cell-specific targeting;
  • polymer-based system;
  • lipid-based system

Summary

This chapter summarizes the roles of siRNAs and miRNAs in several common liver diseases including viral hepatitis, hepatocellular carcinoma, and liver fibrosis. Various delivery systems for siRNA and miRNA are also reviewed.