Endogenous versus Reactive
Published Online: 23 JAN 2015
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
The Encyclopedia of Clinical Psychology
How to Cite
Overstreet, C., Hawn, S. and Amstadter, A. 2015. Endogenous versus Reactive. The Encyclopedia of Clinical Psychology. 1–5.
- Published Online: 23 JAN 2015
This entry examines the evolution of the classification of depression from the endogenous-reactive model, which proposed that the causal sources were either internal (brain based/biological) or external (a reaction to a stressful life event) to the integrative model that is widely accepted today. The original concept's historical roots are briefly summarized, followed by a discussion of several lines of genetically informed research that have shed light on the etiologic sources of psychiatric conditions such as depression and posttraumatic stress disorder. More specifically, gene-environment correlation (rGE) research has aided in the shift away from the once commonly held belief that depression was dichotomously categorized into endogenous (biological) or reactive (environmental) forms.
- post-traumatic stress disorder (PTSD)