19. Anaerobic Fermentations for the Production of Acetic and Butyric Acids

  1. Shang-Tian Yang1,
  2. Hesham A El-Enshasy2 and
  3. Nuttha Thongchul3
  1. Shang-Tian Yang,
  2. Mingrui Yu,
  3. Wei-Lun Chang and
  4. I-Ching Tang

Published Online: 12 JUL 2013

DOI: 10.1002/9781118642047.ch19

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers

How to Cite

Yang, S.-T., Yu, M., Chang, W.-L. and Tang, I.-C. (2013) Anaerobic Fermentations for the Production of Acetic and Butyric Acids, in Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers (eds S.-T. Yang, H. A. El-Enshasy and N. Thongchul), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118642047.ch19

Editor Information

  1. 1

    William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA

  2. 2

    Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), Johor Bahru, Johor, Malaysia

  3. 3

    Institute of Biotechnology and Genetic Engineering, Chulalongkorn University, Bangkok, Thailand

Publication History

  1. Published Online: 12 JUL 2013

ISBN Information

Print ISBN: 9780470541951

Online ISBN: 9781118642047

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Keywords:

  • acetic acid;
  • anaerobic fermentations;
  • butyric acid;
  • distillation;
  • homoacetogenic fermentation;
  • metabolic engineering;
  • microbial production

Summary

This chapter provides a review on recent advances in the development of bioprocesses for butyric and acetic acids production, highlighting metabolic engineering in strain development and novel bioreactor and separation technologies in process development leading to their commercial applications in the near future. Acetic acid is produced naturally as the sole or main fermentation product by anaerobic homoacetogens and aerobic acetic acid bacteria. Metabolic engineering has been widely used in strain development for industrial fermentation to produce bio-based chemicals and biofuels. Conventional batch fermentation processes for acetic and butyric acid production are limited by low reactor productivity, low product yield, and low final product concentration, making product recovery difficult and the process uneconomical. Current petroleum-based manufacturing processes for acetic acid and butyric acid production use distillation for their recovery and purification.