21. Biotechnological Development for the Production of 1,3-Propanediol and 2,3-Butanediol

  1. Shang-Tian Yang1,
  2. Hesham A El-Enshasy2 and
  3. Nuttha Thongchul3
  1. Youngsoon Um and
  2. Kyung-Duk Kim

Published Online: 12 JUL 2013

DOI: 10.1002/9781118642047.ch21

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers

How to Cite

Um, Y. and Kim, K.-D. (2013) Biotechnological Development for the Production of 1,3-Propanediol and 2,3-Butanediol, in Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers (eds S.-T. Yang, H. A. El-Enshasy and N. Thongchul), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118642047.ch21

Editor Information

  1. 1

    William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA

  2. 2

    Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), Johor Bahru, Johor, Malaysia

  3. 3

    Institute of Biotechnology and Genetic Engineering, Chulalongkorn University, Bangkok, Thailand

Publication History

  1. Published Online: 12 JUL 2013

ISBN Information

Print ISBN: 9780470541951

Online ISBN: 9781118642047

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Keywords:

  • 1,3-propanediol;
  • 2,3-butanediol;
  • biotechnological development;
  • Clostridium species;
  • genetic modification;
  • glycerol;
  • Klebsiella species;
  • lignocellulosic materials;
  • microbial production

Summary

This chapter reviews the principles of microbial production of 1,3-propanediol and 2,3-butanediol, and the recent developments for the production of 1,3-propanediol and 2,3-butanediol. It describes 1,3-propanediol production with Klebsiella species, Clostridium species, and other microorganisms, including metabolically engineered bacteria. Recent development in gene sequencing and genetic modification tools has made it more feasible to construct heterologous genes of a 1,3-propanediol pathway. Wood and agricultural biomass (i.e. lignocellulosic materials) are popular candidates for low-price biomass resources, and there has been an increased interest in research on their use for 2,3-butanediol production. The production of 2,3-butanediol from lignocellulosic wastes other than purified hexose and pentose, has been considered as an economical method. Glycerol is also considered to be a cost-effective and efficient carbon source for the production 2,3-butanediol.