19. Hemicrania Continua

  1. Matthew S. Robbins MD,
  2. Brian M. Grosberg MD and
  3. Richard B. Lipton MD
  1. Uri Napchan

Published Online: 19 JUL 2013

DOI: 10.1002/9781118678961.ch19



How to Cite

Napchan, U. (2013) Hemicrania Continua, in Headache (eds M. S. Robbins, B. M. Grosberg and R. B. Lipton), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118678961.ch19

Editor Information

  1. Montefi ore Headache Center, Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA

Author Information

  1. Middletown Medical, Middletown, NY, USA

Publication History

  1. Published Online: 19 JUL 2013
  2. Published Print: 30 SEP 2013

ISBN Information

Print ISBN: 9780470654729

Online ISBN: 9781118678961



  • Hemicrania continua;
  • indomethacin;
  • chronic daily headache;
  • trigeminal autonomic cephalalgias;
  • classification;
  • indotest;
  • cranial autonomic symptoms;
  • posterior hypothalamus;
  • dorsal pons


Hemicrania continua is a primary headache disorder responsive to indomethacin characterized by a continuous side-locked headache associated with superimposed exacerbations and ipsilateral autonomic features. Hemicrania continua can be divided into continuous or remitting forms. It is a relatively rare form of chronic daily headache, although debate exists whether it may be more nosologically similar to the trigeminal autonomic cephalalgias. A work up for secondary headache is usually warranted. The etiology remains unknown, although activation of the pons and posterior hypothalamus has been demonstrated. The disorder may also respond to other non-steroidal anti-inflammatory drugs or typical migraine medications.