12. Avoiding the Use of Hazardous Substances: Substitution and Alternatives

  1. Peter Fisk

Published Online: 1 NOV 2013

DOI: 10.1002/9781118683989.ch12

Chemical Risk Assessment

Chemical Risk Assessment

How to Cite

Fisk, P. (2013) Avoiding the Use of Hazardous Substances: Substitution and Alternatives, in Chemical Risk Assessment, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118683989.ch12

Publication History

  1. Published Online: 1 NOV 2013
  2. Published Print: 13 DEC 2013

ISBN Information

Print ISBN: 9781119953685

Online ISBN: 9781118683989



  • REACH;
  • Green chemistry;
  • alternatives;
  • replacement of use;
  • reduce hazard;
  • substitution;
  • sustainability;
  • process design;
  • regulation


Substances are typically used in the chemical industry either as intermediates in a Consideration of the most acceptable method of meeting a need in respect of health, safety and environmental acceptability is becoming increasingly important. This chapter expands on these principles, focusing on the end product. This is a clear objective of the REACH regulation to reduce the use of hazardous substances. Companies with a responsible attitude towards health and environmental safety will always prefer to use less hazardous substances, when an alternative exists.