20. Reusable Catalysts for Copper-Mediated Cross-Coupling Reactions under Heterogeneous Conditions

  1. Gwilherm Evano1 and
  2. Nicolas Blanchard2
  1. Zhiyong Wang,
  2. Changfeng Wan and
  3. Ye Wang

Published Online: 4 OCT 2013

DOI: 10.1002/9781118690659.ch20

Copper-Mediated Cross-Coupling Reactions

Copper-Mediated Cross-Coupling Reactions

How to Cite

Wang, Z., Wan, C. and Wang, Y. (2013) Reusable Catalysts for Copper-Mediated Cross-Coupling Reactions under Heterogeneous Conditions, in Copper-Mediated Cross-Coupling Reactions (eds G. Evano and N. Blanchard), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118690659.ch20

Editor Information

  1. 1

    Laboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université Libre de Bruxelles, Brussels, Belgium

  2. 2

    Université de Strasbourg, Ecole Européenne de Chimie, Polymères et Matériaux, Laboratoire de Chimie Moléculaire associé au CNRS, Strasbourg, France

Publication History

  1. Published Online: 4 OCT 2013
  2. Published Print: 25 OCT 2013

ISBN Information

Print ISBN: 9781118060452

Online ISBN: 9781118690659

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Keywords:

  • C-C bond formation;
  • C-N bond formation;
  • C-O bond formation;
  • C—Se bond formation;
  • copper nanoparticle-catalyzed cross-coupling reactions;
  • copper-catalyzed coupling reactions;
  • reusable catalysts

Summary

This chapter provides a general analysis and discusses recent advances in heterogeneous copper-catalyzed coupling reactions. In the first section, key bond disconnections (C—C, C—N, C—O, C—S, and C—Se) will be discussed using copper nanoparticle-catalyzed cross couplings, and a second section will focus on the use of supported copper catalysts with an emphasis on the synthesis, recovery, and reuse of these promising catalytic systems. The diaryl ether moiety is a common structural unit widely found in biologically active molecules and natural products as well as in monomers for the synthesis of functional polymers. The oxidative homocoupling of terminal alkynes is an important kind of reaction for C—C bond formation in organic synthesis yielding the corresponding symmetrical 1,3-diynes. The Ullmann coupling for C—O bond formation catalyzed by supported copper catalysts has also attracted the attention of numerous research groups in the past years.