6. Osteoblasts of Craniofacial Bone

  1. Laurie K. McCauley DDS, PhD and
  2. Martha J. Somerman DDS, PhD
  1. Renny T. Franceschi,
  2. Chunxi Ge and
  3. Christopher G. Wilson

Published Online: 5 APR 2013

DOI: 10.1002/9781118704868.ch6

Mineralized Tissues in Oral and Craniofacial Science

Mineralized Tissues in Oral and Craniofacial Science

How to Cite

Franceschi, R. T., Ge, C. and Wilson, C. G. (2012) Osteoblasts of Craniofacial Bone, in Mineralized Tissues in Oral and Craniofacial Science (eds L. K. McCauley and M. J. Somerman), John Wiley & Sons, Inc.,, West Sussex, UK. doi: 10.1002/9781118704868.ch6

Publication History

  1. Published Online: 5 APR 2013
  2. Published Print: 1 MAY 2012

ISBN Information

Print ISBN: 9780470958339

Online ISBN: 9781118704868



  • Bone repair and remodeling;
  • Cleidocranial dysplasia (CCD);
  • Cranial neural crest cells (NCCs);
  • Craniofacial bone;
  • Mature osteoblasts and osteocytes;
  • Mitogen-activated protein kinase (MAPK) pathways;
  • Osteoblasts (OBs);
  • Phosphate homeostasis;
  • Transcriptional control;
  • Wnt pathway


This chapter contains sections titled:

  • Embryological Origin of Craniofacial Osteoblasts From Neural Crest and Specification of Cellular Fate

  • Transcriptional Control of the Osteoblast Lineage

  • Properties of Mature Osteoblasts and Osteocytes

  • Major Regulatory Functions of Osteoblasts and Osteocytes

  • Signaling Pathways Affecting Osteoblast Function

  • Use of Osteoblasts and Osteoprogenitors for Cranial Bone Regeneration

  • Summary and Future Directions

  • Acknowledgments

  • References