22. Atopy Patch Testing for Food Allergies

  1. Dean D. Metcalfe MD2,
  2. Hugh A. Sampson MD3,
  3. Ronald A. Simon MD4,5 and
  4. Gideon Lack MBBCh (Oxon), MA (Oxon), FRCPCH6
  1. Von Ta and
  2. Kari Nadeau

Published Online: 24 FEB 2014

DOI: 10.1002/9781118744185.ch22

Food Allergy: Adverse Reactions to Foods and Food Additives, Fifth Edition

Food Allergy: Adverse Reactions to Foods and Food Additives, Fifth Edition

How to Cite

Ta, V. and Nadeau, K. (2013) Atopy Patch Testing for Food Allergies, in Food Allergy: Adverse Reactions to Foods and Food Additives, Fifth Edition (eds D. D. Metcalfe, H. A. Sampson, R. A. Simon and G. Lack), John Wiley & Sons Ltd, Chichester, UK. doi: 10.1002/9781118744185.ch22

Editor Information

  1. 2

    Chief, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

  2. 3

    Kurt Hirschhorn Professor of Pediatrics, Dean for Translational Biomedical Sciences, Director, Jaffe Food Allergy Institute Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA

  3. 4

    Head, Division of Allergy, Asthma and Immunology, Scripps Clinic, San Diego, CA, USA

  4. 5

    Adjunct Professor, Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA, USA

  5. 6

    Professor of Paediatric Allergy, King's College London Clinical Lead for Allergy Service, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK

Author Information

  1. Division of Immunology and Allergy, Stanford Medical School, Stanford, CA, USA

Publication History

  1. Published Online: 24 FEB 2014
  2. Published Print: 10 DEC 2013

ISBN Information

Print ISBN: 9780470672556

Online ISBN: 9781118744185



  • food allergy;
  • serum immunoglobulin E antibodies (IgE);
  • skin prick test;
  • double-blinded placebo-controlled food challenges;
  • gastrointestinal symptoms;
  • atopy patch test;
  • cutaneous cell-mediated;
  • skin contact;
  • atopic eczema;
  • eosinophilic esophagitis;
  • dermatitis;
  • aeroallergens;
  • food protein-induced enterocolitis syndrome


The current role of food atopy patch testing (APT) in the daily diagnostic workup of suspected food-related symptoms can be useful, but the clinical relevance of a positive APT reaction is still to be proven by standardized outcome definitions. In selected cases, the combination of a positive APT together with other allergy diagnostic tests may enhance management of atopic diseases. APT is time-consuming and demands a highly experienced evaluator.